BLOOMFIELD HILLS – Great Lakes Angels announced that one of

its portfolio companies, Blaze Medical, is now generating revenue.

Blaze, an Ann Arbor-based company, is developing

novel blood analysis technologies, announced that it has begun offering blood

fragility analysis services for pharmaceutical and medical device companies.

Developers of drugs and blood-contacting devices often need to assess the

impacts of their products on red blood cell (RBC) membranes, for evaluating

their products’ safety and/or efficacy. This generally includes looking at

levels of hemolysis – RBC rupture – but that unfortunately fails to reflect any “hidden” or sub-hemolytic cell damage.

Blaze’s proprietary technology solves this longstanding problem by facilitating

measurements of RBC mechanical fragility (MF) – a more precise metric of blood

damage than simple hemolysis. It’s also an important parameter in calibrating

for hemolysis measurements. While Blaze is developing its first fully integrated

and automated Fragilimeter system for academic and industrial research

customers, it also now offers RBC mechanical fragility testing on a service

contract basis.

“This move was in direct response to industry demand and highlights industry

interest in exploiting the advantages of this metric,” said David Weaver, CEO

of Blaze and president of Great Lakes Angels. “Our first contract began in late

2014. Since then, we expanded our service capacity and signed our second

customer, with more contracts in negotiation.”